Antimicrobial resistance (AMR) is an urgent global health crisis, characterized by the reduced efficacy of antimicrobials such as antibiotics, antiviral, antifungal, and antiparasitic drugs due to misuse and overuse. This resistance poses a significant threat to human, animal, and environmental health, leading to increased mortality rates, prolonged illnesses, and significant economic burdens. This article discusses the causes, impacts, and key drivers of AMR, emphasizing the interconnectedness of human and animal health. It highlights critical measures, including rational drug use, improved infection prevention, public awareness, and investment in new drug development, to combat this growing threat. Immediate collective action is needed to prevent a return to the pre-antibiotic era.

Key Words: Antimicrobial Resistance, Antibiotics, Global Health, One Health, Infection Control